Cover Feature: Ferrier/Aza‐Wacker/Epoxidation/Glycosylation (FAWEG) Sequence to Access 1,2‐<i>Trans</i> 3‐Amino‐3‐deoxyglycosides (Chem. Eur. J. 17/2023)
نویسندگان
چکیده
Travelling without moving. A Ferrier rearrangement on commercial glycals brings the double bond from position 1,2 to 2,3. Subsequent Aza-Wacker reaction allows both a 3,4-cis amination at 3 and movement of restoring glycal. These motions, reminiscent swing, enable synthesis 3-amino-3-deoxyglycals. Epoxidation/Glycosylation 3-amino-3-deoxygalactal derivative provide disaccharide with high yield, defining “FAWEG” as new sequence access 1,2-trans 3-amino-3-deoxyglycosides. More information can be found in Research Article by A. Joosten co-workers (DOI: 10.1002/chem.202203987).
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ژورنال
عنوان ژورنال: Chemistry: A European Journal
سال: 2023
ISSN: ['0947-6539', '1521-3765']
DOI: https://doi.org/10.1002/chem.202300533